Beilstein J. Org. Chem.2022,18, 926–934, doi:10.3762/bjoc.18.92
and substituents was also studied during investigation of fluorescence properties of these derivatives.
Keywords: β-carboline; DABCO; fluorescence; MBH reaction; Michael addition; structure–fluorescenceactivityrelationship; Introduction
Among the polycyclic alkaloids based on indole, the tricyclic
structure–fluorescenceactivityrelationship of C-3 substituted pyrido[3,4-b]indole derivatives 7, 8 and 10.
Synthesis of 3-formyl-9H-pyrido[3,4-b]indole derivatives.
Synthesis of C-3 substituted pyrido[3,4-b]indole MBH derivatives (7 and 8).
Synthesis of C-3 substituted pyrido[3,4-b]indole MBH derivatives
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Graphical Abstract
Figure 1:
Few examples of β-carboline-based drugs and bioactive natural products.